Alpha Lipoic Acid- In first clinical trials, alpha-lipoic acid (ALA), managed to restore full liver function to 95% of the acute and severe liver damaged patients, when administered intravenously. Curative effects of ALA have been defined by the modulative regulation in eukaryotes. Lipoic acid has shown the ability to promote and boost the absorption of glucose to cell membranes; furthermore laboratory studies have shown that it can reduce triglycerides in blood. Besides the obviously high efficacy as an antioxidant, ALA has shown to be able to prevent vitamin C and vitamin E deficiency, the use as a chelator is still in the test phase; ALA in combination with L-carnitine shows improved mental performances in tests, paired with a postponed structural mitochondrial decay, making it a candidate in combating Alzheimer’s and Parkinson’s diseases.

Bioperine is a convenient and concentrated form of black pepper’s ingredient called piperine. Bioperine enhances bioavailability and absorption. Bioperine is a safe and pure nutritional piperine supplement. This is an alkaloid that is available from the fruits. Piperine is responsible for the ability of pepper to enhance the nutrients bioavailability. 95% piperine is present in Bioperine. Black pepper was popular as it was the most desired spice. The black pepper was useful in ayurvedic medicine as it increased the food digestibility. The pepper consumption shows positive indication by generating internal heat. The nutritional status is based on a person and his eating style. Bioperine enhances the heat production in the body and this result in food digestion and eventually the energy is used. Bioperine facilitates the bioavailability of nutrients in a broad range. Bioperine is considered to be a thermogenic local agent as it increases the thermogenic reactions. Bioperine is an apposite nutritional supplement identical to pepper that is to food.

Caffeine, a central nervous system stimulant used in Thermoloid as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

L-Carnitine is chemically similar to an amino acid, L-Carnitine is responsible for the metabolism of fat in the body. It transports fatty acids into the cell’s metabolic furnace known as mitochondria. Synthesized in the liver and kidney, L-Carnitine helps the body use fat for energy. It acts as an aid in releasing tryglycerides and stored body fat into the bloodstream. With an adequate intake of L-Carnitine, you can improve the contraction of muscles, function of the heart and balance of protein in the body. As compared to the synthetic fat burning supplements that cause insomnia and addiction, L-Carnitine is a natural component which brings fat to metabolizing stations so that it can burn and produce energy. In case you have carnitine deficiency, you can have 1000mg of tartrate per day which is considered to be an effective form of carnitine.

Synthetic Guggulsterones are derived from a herb, commiphora mukul, which has been proven to restore lagging metabolic rate brought about by dietary caloric deficiency, such as a diet low in carbohydrates. Though it has cholesterol lowering ability, it is also known as powerful weight loss agent due to the increased conversion of the inactive thyroid hormone T4 into its active part T3 in the liver. Furthermore, Guggulsterones are also known to stimulate the thyroid directly by enhancing TSH (Thyroid Stimulating Hormone) production. This is especially true for two specific guggulsterones codenamed Z and E.

White Willow Bark, less commonly known as salix alba, is extracted from a plant native to Europe and parts of Asia. The great physician Hippocrates first mentioned the use of White willow extract in his writings in 5th century BC and it has been touted as a powerful supplement for several different uses ever since. It is commonly used as a pain reliever (particularly for back pain and arthritis), fever reducer, and inflammation reducer. Although aspirin was eventually invented using the same base as White willow extract, many purists and natural health enthusiasts prefer to use White willow extract, which is considered to be nature’s aspirin.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.