1-Methylcaffeine is a derivative of caffeine and is a compound with a two ringed structure. It occurs naturally in several beverages or can also be prepared by chemical treatment of Caffeine under strictly controlled conditions of temperature and pressure. Like caffeine, it too is usually used or mixed in order to increase mental awareness, relaxing tensed muscles and stimulation of cardiac muscles among others. It is also commonly used for controlled change in the concentration of intracellular calcium and in resisting the activity of adenosine receptors. It is often used by athletes to reduce muscle strain and for mild water based weight gain for short term. It also helps increase the rate of heartbeat thereby increasing the bloodflow to the cells and increasing the amount of energy produced in the body.

11-Hydroxy Yohimbine is available as extract and is reported to have toxic effects. It contains alkaloids to ten or fifteen percent. The Hydroxy Yohimbine is considered to be pure than the Herbal Yohimbine extract. Hydroxy Yohimbine extract is regarded to be safer and consistent. This is found in trees and is used as medicine to treat erectile dysfunction. Hydroxy Yohimbine is also useful in treating obesity. The common side effect is anxiety. Hence, people prone to panic attacks are recommended to avoid using Hydroxy Yohimbine. People facing disorders due to stress also should avoid Hydroxy Yohimbine. Hydroxy Yohimbine in combination with other drugs increases the nitric oxide action. For erectile dysfunction treatment Hydroxy Yohimbine should be taken 0.1 milligram/kg daily. It is best before meals, especially when the stomach is completely empty. Hydroxy Yohimbine is also a weight loss agent as it burns fat.

Alpha-Yohimbine works with potent MAOI-inhibiting properties. In this context, it basically works like an amphetamine-potentiator, as it stops the neuro-breakdown of dopamine, noradrenaline and serotonin. Having similar alpha-2 antagonistic properties to yohimbine HCI, it is also less vasoconstrictive in areas, making it less likely for inducing increase in BP. It is an analogue of yohimbine, however there is a difference in its potency at the subreceptors of alpha2, most notably at alpha2c adrenergic and alpha2b subreceptors. This is 4 times more potent alpha2c and 3 times more potent at alpha2b. Yohimbine is an alkaloid which is found in a tree’s inner bark which grows in Southern Africa. It has been in use for centuries as an aphrodisiac. Today, it is primarily used in veterinary medicines and also for the treatment of erectile dysfunction. It is also used in treating obesity.

B-Phenylethylamine HCL is known to be a perfect stimulant and strong mood enhancer. It is extremely efficient in enhancing body metabolism by allowing you to burn more calories and accumulated fat at a faster pace. Unlike many other stimulants, B-Phenylethylamine does its job without causing any negative side effects like negative side effects like nervousness, anxiety or some slight headaches. It’s major ingredient Phenylethylamine gets metabolized by “monamine oxidase” (MAO). This enzyme thwarts all but the slightest amounts of Phenylethylamine from entering the bloodstream. Being a Phenylethylamine based fat burner, it contains natural monamone oxidase inhibitors that prevent these side effects.

Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Methylsynephrine is a variation of B – phenylehylamine which is found in the rare medicinal plant Acacia Rigidula and some other cacti which basically produces central nervous stimulation. Methylsynephrine is one of the newly identified key alkaloids in Acacia Rigidula. Methylsynephrine is an off the chain version of Synephrine. It is an adrenergic amine which accelerates fat metabolism as well as thermogenisis. These simultaneously speed up the fat burning process. Methylsynephrine, unlike ephedrine which is chemically similar, has mild stimulating properties on the central nervous system. This is a very desirable property in any weight loss compound as it allows for quick fat burning without the accompanying racing hear and anxiety. Methylsynephrine is also distinctive due to its role in the metabolization and the destruction of fat in the body by freeing up the stored fat for energy instead of using the ingested carbohydrates.

N-Methyl-B-Pheylethylamine HCL is one of the various compounds got from Acacia Rigidula. It reduces fat in the body and increases the production of energy on a large scale. It is a fantastic compound that is a catecholamine precursor and even a nutrient available in chocolate even in its purest of forms. It produces simulation in the CNS (Central Nervous System) without giving rise to the jittery feelings or nervousness that occurs when some other drug is used. It acts on the alpha receptors present in the brain, resulting in release of the chemical, dopamine, which gives a good feeling. PEA is a compound that promotes focus, concentration and alertness of the mind. It can even elevate the metabolic rate of a person that causes increased fat burning. However, it is rapidly metabolized and crosses the blood-brain barrier in smaller proportions. This chemical is a potent wonder but, as with most chemical drugs, it is safe to take small and restricted measures just to be safe.

R-Beta-Methylphenylethylamine HCL is a relatively new compound which is the active isomer of Methylphenylethylamine similar to how 1R-25 Norephedrine was of PPA many years ago. What makes R-Beta-Methylphenylethylamine HCL very popular and an important component for many commercially produced weight loss products is to do with the effects it has on the human body. R-Beta-Methylphenylethylamine HCL is a compound which stimulates norepinephrine unlike any other compound in the body. By stimulating norepinehrine, R-Beta-Methylphenylethylamine HCL produces effects like appetite suppression, increase in energy and through the combination of these two effects, there is an overall result of weight loss.

Synephrine, More commonly called "bitter orange" or Citrus Aurantium, which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Yohimbine HCL is the active chemical component of the medicinal herb Pausinystalia yohimbe. It is a stimulant drug and is reportedly an aphrodisiac. According to the National Institute of Health (NIH), the standardised form of this chemical is Yohimbine hydrochloride (HCL) and is available as a prescription drug in the United States. Research has shown that yohimbine hydrochloride is effective as a treatment for male impotence. However while yohimbine HCL has been used as a prescription medicine to treat erectile dysfunction controlled studies suggests conflicting results. Apart from male sexual dysfunction, yohimbine HCL has also been used to treat the side effects of antidepressants like female hyposexual disorder etc. It is also used to recall memories in the treatment of post-traumatic-stress-disorder. While there are several uses for yohimbine HCL, there are several side effects too. These include high blood pressure, insomnia, panic attacks, hallucinations, headaches, renal failure, heart disease etc.