Caffeine, a central nervous system stimulant used in Estrin-D as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Ginger Root has been used as herbal medicine in India, Asia, and Arab countries for a long time. People in China have been using this knotted, thick, underground stem or rhizome of the plant Zingiber officinale to improve digestion for over two thousand years. Ginger was also found effective in the treatment of health conditions such as heart problems, arthritis, colic, and diarrhea. Ginger is also a popular cooking spice in different cuisines. The magic herb can also help a great deal in pregnancy, motion sickness, and cancer chemotherapy since it aids in preventing or treating nausea and vomiting associated with it. Many women consume ginger to reduce the pain during menstrual periods. Ginger is also used to reduce inflammation and combat inflammation-related problems such as arthritis and ulcerative colitis. You may buy fresh ginger root or go for other variations like ginger extracts, capsules, and oils.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana is a South American climbing plant belonging to the genus of trees and shrubs called Maple. This plant is common around the Amazon and very present in Brazil. The fruit of the guarana plant is being used in that country to produce a diversity of soft drinks and beverages, having the double caffeine content of the coffee bean. Other nutrients that are contained in the seed besides caffeine are protein, fat and starch, but also adenine, choline, guanine, resin, tannin and xanthine, just to name a few. The cognitive effects of guarana are well documented, but the appetite suppressant qualities of guarana are relatively new. A study has proven that a combination of yerba mate, guarana and damiana leads to a tenfold weight loss quantity when compared with a placebo.

Kola Nut is native to Africa, mainly found in the tropical rain forests. There are about hundred and twenty tree species which belong to this family, their fruit, the kola nut, being the interesting feature. It has been traditionally used for chewing, with an effect where hunger cravings subsided. The popularity of the kola nut was established by The Coca-Cola Company, which used the kola nut as an ingredient in this popular drink. Many other similar drinks and also energy drinks feature this ingredient. The kola nut, although featuring caffeine, provides a xanthine mixture with catechins which not only stimulate the central nervous system but also has analeptic and lipolytic properties, as well as chronotropic effects. Further effects include enhanced alertness, physical energy, mood and tactile sensitivity, as well as appetite suppression.

Some Unknown Ingredients, which is a common practice for many supplement manufacturers. They use ineffective common ingredients and trademark their name for them to disguse the actual low quality ingredient contained.

Yerba Matte- Described as an ancient drink of friendship derived from a small shrub. It is sometimes spelled as yerba mate and people drink it in order to gain energy producing properties without consuming caffeine as they would in normal tea or coffee. People believe that yerba mate is a appetite suppressant, clears the mind as well as relieving allergies, improving sleep patterns and lifting the mood, that is why it is used in Estrin-D. It is advertised as an aid to weight loss, a fortifier of the immune system, a colon cleanser and even as a means of extending life. It is prepared as an infusion, with twigs and leaves immersed in boiling water in order to produce a tisane. Traditionally it is made in a vessel which is then shared among friends.