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AAKG is a kind of salt, amino salt to be precise that is being used in dietary and even body building supplement. The protein content that Alpha-Ketoglutarate produces is the ones responsible for producing different hormones that are responsible for muscle growth. Please take note that this is not something that can be compared with steroids. Alpha-Ketoglutarate just helps your body produce the right amount of body building hormones – it basically maintains the body system’s entire metabolic process. For people who have recently undergone surgery, this is what most surgeons recommend. It increases the level of insulin in the body and increased insulin means faster cell regeneration and faster wound healing.
Betaine was named this due to the source it was discovered in, Beta vulgaris or sugar beets, is an organic compound that is deemed related to trimethylaminoethanol, or choline. To diversify it from other betaines, trimethylglycine is often called glycine betaine as well. Humans generally ingest betaine through their diet, because it is high in content in wheat, whole wheat, shellfish, sugar beets and spinach. It can also be formed in the human body out of choline. As a potential methyl donor, trimethylglycine, or TMG for short, is in the same provider group with Vitamin B12, the folic acid, choline and S-adenosyl methionine, or SAMe. TMG also plays a vital function in the production of carnitine, furthermore it works in protecting kidneys and the liver.
Biotin, also called Vitamin H or Vitamin B7. Biotin is a water-soluble B-Complex Vitamin that is needed for the metabolism of fats, carbohydrates and proteins.
Calcium, a mineral vital to the human body, Calcium is necessary for many bodily functions, such as muscle contraction, and proper heart function.
Choline- Grouped with the Vitamin B complex, choline is deemed an essential nutrient. It is a natural amine and an organic compound, which serves several physiological purposes. Choline improves the structural integrity of cell membranes and provides signaling roles, assisting with the system of communication, which controls basic cellular activities and manages cell actions. Deemed a nootropic drug, choline as a dietary supplement is supposed to increase the cognitive behaviour and alertness. As a building block of the neurotransmitter acetylcholine, choline certainly seems to be nootropic, but recently the application of choline as a nutritional supplement helping to reduce body fat because of the activity in the lipid metabolism was observed. Infant formulas that are not derived from cow’s milk are ordered by the FDA to supplement choline.
Chromium.
Copper is being considered a mineral with immense medical advantages, copper has been used as a supplement in its gluconate form. Copper is one of the most important constituents of the blood and prevents poly – unsaturated fatty acids from turning rancid. Copper also increases the health of the cell membranes and is actively involved in the formation of hemoglobin.
Copper Gluconate is instrumental in treating conditions such as irregular beating of the heart, hypoglycemia, osteoporosis, osteoarthritis, and in lowering the cholesterol levels of the body.
Copper Gluconate is known to have side effects and is toxic if taken excessively. In the case of women who are expecting or mothers who are nursing, it is advisable to consult with your docter before taking any Copper based supplements.
Glycocyamine was sought after because as much as a quarter of the world’s population is unable to supplement creatine, more accurately, the supplementation of regular creatine monohydrate had no effect whatsoever. Glycocyamine is a creatine metabolite, missing just a methyl group. Glycocyamine is guanidinoacetic acid and creatine is methylguanidinoacetic acid. Interestingly enough, glycocyamine is processed by the liver and metabolized into creatine, which allowed the rest of the world to supplement creatine as well. Unfortunately the supplementation of glycocyamine also meant that many methyl groups otherwise needed by the body would be now used up by the synthesis of creatine. For that reason it is generally recommended to supplement glycocyamine together with betaine, in order to provide enough methyl groups for all purposes. The commonly suggested ration is four parts betaine, one part glycocyamine, hence a four to one ratio.
Iodine, a necessary element used by the body to make the thyroid hormones thyroxine and triiodothyronine. These Thyroid hormones are needed to maintain a healthy metabolic rate and cellular metabolism.
Iron is vital in human nutrition as the adult human body contains 3-4 grams of iron. Haem-iron and non-haem iron are the two types of iron. Foods rich in haem-iron include meat, liver, fish, and poultry. Foods that are high in non-haem iron are those of vegetable origin, like green leafy vegetables, cereals, legumes, oilseeds, nuts, dry fruits and jiggery. Iron is vital for numerous body functions, including hemoglobin formation, brain development and function, muscle activity, regulation of body temperature and catecholamine. Deficiency of iron affects immune system, reduces the number of T-cells and production of antibodies. Iron is also necessary for binding oxygen to body cells as its main function is oxygen transport and cell respiration. It works as an anti-cancer agent. Iron increases energy level of the body, improving physical performance. It prevents insomnia.
L-Isoleucine is an essential alpha-amino acid that is considered both, a ketogenic and a glucogenic amino acid. Since that L-Isoleucine is an essential amino acid, it cannot be synthesized by the body, therefore it needs to be ingested. The primary source of L-Isoleucine is as a component of proteins. It has become a prominent component of nutritional supplements, mostly with the body building and similar athletic communities, where it is believed that L-Isoleucine has the capability to increase endurance, but also to repair muscle tissue. It has been observed that L-Isoleucine ingestion allows power athletes to recover easier from very tough trainings and exhausting activities. This branched chain amino acid is one of the three main BCAA in the body, the other ones being valine and leucine.
L-Leucine, is an alpha amino acid which is extremely essential in the everyday functioning of the body. Leucine is also an essential amino acid, meaning that the human body cannot synthesize it and it has to be ingested. And is found in brown rice, nuts and whole wheat bread products.
L-Leucine as an essential amino acid increases the synthesis of muscle protein and thus slows the degradation of muscle tissue. L-Leucine is also utilised in the liver, adipose tissue and muscle tissue. Simply put, L-Leucine supplies the body with energy when engaging in an athletic activity, it preserves the glucose stored in muscle tissue and it works to heal bone, skin and muscle tissue. It is also a ‘limiting nutrient’ thus it helps the body make use of the proteins ingested.
Leucine deficiency can lead to depression, muscle weakness, low energy etc.
L-Lysine- Lysine is an essential alpha amino acid that needs to be ingested and cannot be synthesized by the human body. Sources of L-Lysine include meat, particularly red meat, lamb, poultry and pork, but also cheeses, like parmesan, some fish like cod and sardines and eggs. Several plants are rich in L-Lysine, soybean, lentil, spinach and buckwheat, but also buffalo gourd, watercress, locust bean and many other bean variants, including the common bean. L-Lysine is deemed vital for the overall production of protein, as a structural building block. It seems that L-Lysine also plays a prominent part in the absorption of calcium. Further properties include playing a role in the production of enzymes, hormones and antibodies, but also in the recovery from sports injuries and surgeries.
L-Methionine- Methionine is a nonpolar essential alpha amino acid containing sulfur; one of only two proteinogenic amino acids besides cysteine. Methionine is vital to several biosynthesis processes of phospholipids as an intermediate, the prominent list includes taurine, lecithin, carnitine, phosphatidylcholine and cysteine, just to name a few. This water soluble antioxidant assists in the lipid breakdown and works against free radicals. Just like many such amino acids, it can be obtained through ingestion of dietary proteins, such as meat, eggs, cheese, fish and poultry, but some levels are also available from spinach, sesame seeds and Brazil nuts. It has been found that an inadequate conversion of methionine may cause atherosclerosis. This glycogenic amino acid is also part of other biochemical reactions, like the creation of S-adenosylmethionine, which in turn is a part of the synthesis of epinephrine, melatonin and creatine, among others.
L-Phenylalanine- The human body needs L-Phenylalanine for survival as it is an essential amino acid. It is found in food items that are rich in protein such as eggs, meat, dairy products, beans and fish. Since the body cannot produce L-Phenylalanine from other chemicals, you need to increase the intake of protein for fulfilling the nutritional needs. L-Phenylalanine is one of the chemical forms of Phenylalanine, an amino acid.
It helps in building up of several proteins produced by human body. L-Phenylalanine supplements act as an appetite suppressant as it initiates the release of cholecystokinin, an intestinal hormone. Once this hormone enters the stomach, it signals your brain that you are not hungry anymore. According to experts, you should not take more than 500-1000 mg of L-Phenylalanine per day.
L-Threonine- 2-amino-3-hydroxybutanoic acid, or L-Threonine, an enantiomer of Threonine, which is an essential amino acid, needs to be ingested by way of diet, predominantly through Threonine containing proteins. There are two ways how Threonine can be metabolized, namely conversion into pyruvate by utilizing Threonine dehydrogenase, whereby an intermediate can thiolyze with CoA, producing acetyl-CoA and glycine; and the second possibility, where Threonine is changed into alpha-ketobutyrate, utilizing serine dehydratase, towards becoming succinyl-CoA. Succinyl CoA is a CAC intermediate, which means that it is a part of the citric acid cycle. The citric acid cycle is a vital part of the metabolic pathway which is securing the conversion of carbohydrates, proteins and fats towards usable energy. Foods containing Threonine are meat, poultry and fish and related products, cottage cheese, sesame seeds and lentils.
L-Tryptophan- Tryptophan is an essential amino acid as well as within the group of only twenty standard amino acids that are required by the human diet. It is one of the building blocks required for protein biosynthesis. It is also viewed as a precursor to serotonin and thereby also melatonin, niacin and also auxin. Interestingly enough, lactose intolerance and fructose malabsorption have the side effect that tryptophan is only improperly absorbed in the intestines which leads to diminished levels of it in the system. Dietary sources of tryptophan are plentiful, it can be found in red meat, poultry, fish, milk, milk products, peanuts, mangoes, dates, chocolate and oats, among others. As a dietary supplement tryptophan has found applications as a safe sleeping aid and also as a calming agent.
L-Valine is the third branched chain amino acid and is required for muscle metabolism, repairs and regenerates tissue, and maintains the body's nitrogen level. It also is used as a muscle energy source and preserves the use of glucose.
Magnesium, which is a mineral used by the body to help maintain muscles, bones, and nerves. Magnesium is also needed for energy metabolism and protein synthesis.
Niacin is also known as Vitamin B3 or nicotinic acid. It helps in the conversion of carbohydrates into glucose that serves as fuel for energy. It also helps the body in metabolizing fats and proteins. Niacin also helps in the production of hormones necessary for the body to function properly. It is also effective in improving the circulation in the body. It lowers cholesterol, triglycerides and blood sugar level. It also helps in the treatment of coronary artery disease. It also helps in regulating the blood sugar level. Niacin also helps prevent the Pellagra disease, which causes digestive problems, diarrhea, dermatitis, hyper-pigmentation, amnesia, dementia, delirium, and even death. Niacin also helps prevent Alzheimer’s disease, diabetes, and is also effective in treating acne.
Pantothenic Acid, commonly called vitamin B5, is water soluble and is needed by every cell in the body to maintain good health. It helps in breaking down carbohydrates, fats and proteins to provide the body with energy. It assists in the production of red blood cells and hormones and ensures a healthy pregnancy. It is also known to lower triglyceride and cholesterol levels in the body. It helps in reducing stress and treating people with rheumatoid arthritis.
Pantothenic acid is found in small quantities in almost all foods but abundantly in meats, fish, poultry, avocados, peas, broccoli and whole grains. A deficiency which is rare, leads to leg cramps, gastrointestinal problems, anemia, insomnia, depression, a burning sensation in the limbs and a weakened immune system.
Phosphate (Phosphorus) is the chemical element with the atomic number 15 in the periodic table. It is not found as a free element anywhere in the world. In biology and biochemistry it may be the most important element, being present in all living cells of living species. It is present in the DNA, in the RNA, in ATP, but is also found in cell membranes in form of phospholipids. It is also present in the bones, where it builds calcium phosphate salts, responsible for strong bones. Apatite is a collection of phosphate minerals which are generally found in bones and teeth; namely bromapatite, fluorapatite, chlorapatite and hydroxyapatite. Several phosphates are being added to body building supplements and powders, intended to aid in skeletal and cellular strength improvement.
Potassium is an electrolyte, a substance that maintains the fluid levels in the body. It is helpful in regulating blood pressure and heart function. Intake of potassium can benefit people suffering from hypertension. Research has found that a potassium supplement intake decreased incidence of stroke by 60 percent. It neutralizes acids and restores alkaline salts to bloodstream. It acts along with sodium cells to maintain or restore membrane potentials. Potassium is also vital for nerve functioning and cardiovascular, and regulates nutrients’ transfer into cells and adds to muscle energy. It also helps recuperative powers, besides regulating water balance. Potassium is beneficial for eliminating wastes. It is helpful in controlling headaches and convulsions, and quickens healing of cuts, bruises and other injuries.
Riboflavin, also called Vitamin B2, is naturally manufactured by the body. Riboflavin is needed for the proper use of oxygen and amino acids, carbohydrates and fatty acids.
Riboflavin is also utilized by Vitamin B6 in the body and is used to manufacture niacin. Riboflavin is especially needed when eating large amounts of protein.
Sodium is part of the extracellular fluid of many multicellular creatures, not least mankind. It is needed for instance in nerve conduction and to balance the acid levels in the body. It is necessary for the functioning of organs such as the liver, intestine and kidneys in their work of ridding the body of toxins However there is an optimum intake. Above this there are problems such as a rise in the blood pressure. Also an excess of salt in the diet will draw fluid out of the cells by the process of osmosis. On the other hand a lack of sodium will lead to too much water in the body the brains cells will actually be flooded.
Taurine is an amino acid that the body usually has lots of. It can be found both in the nervous system as well as the muscles. Its job amongst other things is to assist in the releasing of brain neurotransmitters.
Thiamine, also called Vitamin B1 or Thiamin, is needed to help the body utilize energy from proteins, fats and carbohydrates.
Thiamine is commonly found in breads and cereals. Thiamine is water-soluble and is concentrated in muscle tissue as it passes thru the body.
Tyrosine is a non essential amino acid derived from several sources, including soy, poultry, milk and cheese products, but can also be synthesized in the body from phenylalanine. There are twenty amino acids that are used in human cells to synthesize proteins, one of which is tyrosine. It is of vital importance to the carbon dioxide conversion into organic compounds conducted by plants, the photosynthesis. Tyrosine is also recognized as a precursor to hormones, but also alkaloids and pigments. It is furthermore viewed as a precursor to neurotransmitters; it increases the levels of plasma neurotransmitters, most prominently norepinephrine and dopamine. While under normal circumstances the effects of tyrosine are inconclusive, it has been observed as useful in stress situations and to reduce the effects of a cold, fatigue, sleep deprivation and any kind of prolonged labor.
Vitamin A- Otherwise known as retinol is the vitamin which helps the eyes to adjust to changes in light levels as well as keeping the eyes, skin and mucous membranes moist. Vitamin A enters the human diet mostly from animal foods, but as well as this some plant foods contain beta-carotene, which the body is then able to convert into Vitamin A. Retinol has antioxidant properties that help the body to repair tissue and cellular damage by neutralizing free radicals.
Although there seems to be some evidence that retinol may help in cases of established artery disease the American Heart Association does not recommend it as a necessary supplement until there is more evidence.
Vitamin B12- Also called Riboflavin, B2 is a water absorbed vitamin of which the body must replenish its supplies each day as it cannot be stored. It is necessary for the production of red blood cells and, like the other B vitamins, it works at supporting it supports energy production by helping in the metabolism of various foods.B2 is required for healthy skin as well as hair growth, the nails and has a role in regulating the activity of the thyroid gland. It is also necessary in order that the body can process amino acids found in proteins and fats and to activate vitamin B6 and folic acid.
Vitamin C is an obvious essential nutrient and a deficiency of this will cause scurvy. It is also an antioxidant and acts as an electron donor for eight different enzymes.
Vitamin D is actually a group of prohormones, all fat soluble, whereby ergocalciferol, or Vitamin D2 and cholecalciferol, also known as Vitamin D3 are the most common forms. The Vitamin D3 form is made when human skin is exposed to UV B radiation. The active form of Vitamin D is calcitrol and it is required in the body to manage phosphorus and calcium levels, but, among other functions, to affect anti tumor activity, immunomodulatory functions and much more. Vitamin D, or more accurately calcitrol, is being bound to a carrier protein, which allows it to be transported throughout the body to the various destinations. The Vitamin D receptors, steroid and thyroid hormone receptors, can be found in most organs, including the brain, skin, heart, breast, prostate and gonads.
Vitamin E, an anti-oxidant nutrient, neutralizes free radicals in the human body to prevent cell damage. This fat-soluble vitamin not only aids the formation of red blood cells but also helps in the absorption of vitamins A, C and K. It is also very helpful to fight various ailments. Since the human body cannot produce vitamin E on its own; it has to be incorporated in our daily diet.
This can be done either by consuming foods that are rich in vitamin E or by taking vitamin E supplements. The RDA for adult males is 10 mg. while 8 mg. is the daily requirement for adult females. Expecting and nursing women should compulsorily take 10 mg. of vitamin E supplements. Vitamin E supplements are most effective when consumed with food.
Zinc is acknowledged as essential to the human organism. It is a trace element found in over a hundred and up to three hundred enzymes. It is the second most important mineral in the body, after iron. Zinc is also defined as an important catalytic agent, which is active in enzymatic reactions such as hydroxilation, which is essential for the protein forming amino acid proline, but also for hypoxia response. Zinc is naturally found in red meat, milk, spinach, nuts, oysters, beans and oats. Low zinc counts can attribute to a weakened immune system, interfere with muscle building, cause diarrhea and all kind of other deficiencies. In body building circles, Zinc is an important supplement, valued for the indirect increment of testosterone and the muscle building role.