Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

Embelic Myrobalan Extract is the extract of a plant with biological name Emblica officinalis. In India it is commonly known as amla. The active ingredients in Emblic myrobalan that have significant pharma-cological action are gallic acid, tannins, pectin, and ascorbic acid (Vitamin C). Its extracts are used in medicine for treatment of vermifuge and to stimulate appetite. It is one of the highest natural sources of Vitamin C (3,000 mg per fruit). Some studies suggest that Emblic myrobalan extracts can be used in treatment of diabetes. Research also shows that it increases the red blood count, strengthens the hair and prevents premature graying of hair.

Evodiamine is a chemical that is extracted from a particular species of plants that has been shown to reduce overall fat intake.

N-Acetyl-L-Tyrosine relates to the supplementation of tyrosine. The N-Acetyl-L-tyrosine is converted into L-tyrosine. N-Acetyl-L-tyrosine is useful in treating depression and mood problems. This is also of immense use in treating blood pressure, skin and hair color as well as Parkinson’s disease. N-Acetyl-L-tyrosine gets converted into the body and is soluble in water. N-Acetyl-L-tyrosine serves as one of the significant supplement to increase the tyrosine levels present in the body because the substances that stay undissolved are un-absorbed by the digestive tract. This contains B-6 vitamin and this is a must for the synthesis for neurotransmitter. N-Acetyl-L-tyrosine is prohibited by the FDA regulations to be appropriate for medical treatment. N-Acetyl-L-tyrosine, in the recent research has come to conclude that it is effective for medical conditions. Even mild stress causes neurotransmitter deficiency and this ends up in sullen moods or depression. However, N-Acetyl-L-tyrosine is useful in restoring skin pigment and also is effective in hair darkening.

Octopamine is a secretion initially discovered in the salivary glands of the Octopus and hence the derivation of the name. it tendso to act as a neurotransmitter, transmitting messages from the neurons to the brain and vice versa. Octopamine has been found to have a tendency to release fat deposits from cells, thus aiding in the loss of weight. It is therefore being used as a slimming agent by most people, even though there is no concrete evidence that it does assist in weight loss, for sure. Octopamine is also believed to increase blood pressure levels when it is in combination with other weight loss stimulating supplements. Although not much is known about Octopamine, a deeper study is being conducted into its uses and effects.

Passion Flower- Passion vines, or Passiflora, are a 500 species strong genus of flowering plants that all belong to the family of Passifloraceae. While most of the plants are classified as vines, there are also some shrubs and herbaceous plants that can be found. With the exception of Europe and Africa, as well as Antarctica, these plants are found all over the rest of the world. While the passion flower is mostly known for the Maracuja, or Passiflora edulis, the passion fruit, the vines of some species in this genus are known to have properties that have been used by Native Americans for treatment of insomnia, epilepsy and hysteria, as noted with Passiflora incarnata. Many other species contain beta carboline harmala alkaloids, which function as monoamine oxidase inhibitors and are powerful antidepressants.

Sclareolide is a terpenoid, commonly won out of salvia sclarea, also called clary sage, which is a biennial herb. It grows predominantly in Europe and in Asia, but is most common in Syria, Italy, Switzerland and France. Sclareolide stimulates adenylite cyclase, which is an enzyme increasing cyclic adenosine monophosphate levels in the body. It actually increases your metabolism rate and turns energy into heat. The overall effect is that you burn more calories, whereby further energy is provided by extraction of fat from their storage spaces. The increased lipolysis leads to removal of excess fat, but also to much leaner physique and better muscle definition. Sclareolide may in excess dosages lead to vasodilatory effects, increasing thereby the blood pressure. Slight antidepressant action may also occur.

Vinpocetine, a derivative alkaloid of vincamine, is actually semi synthetic in nature. It is an extract from the It is an extract from the periwinkle vinca minor. Vinpocentine is used because it has neuroprotective effects and also helps in enhancing the cerebral blood flow. In Eastern Europe, it is also used as a drug to treat cerebrovascular disorders along with age related memory impairment. It is also extensively marketed as a supplement for vasodilation. It is also used to improve the memory since it plays the role of a nootropic. Vinpocentine is therefore used in supporting brain function. It helps in enhancing concentration and memory by activating cerebral metabolism. In the body building world, vinpocetine is often used a vasodilator. However, no research has been done so far on the effect of vinpocentine in the body building.

White Willow Bark, less commonly known as salix alba, is extracted from a plant native to Europe and parts of Asia. The great physician Hippocrates first mentioned the use of White willow extract in his writings in 5th century BC and it has been touted as a powerful supplement for several different uses ever since. It is commonly used as a pain reliever (particularly for back pain and arthritis), fever reducer, and inflammation reducer. Although aspirin was eventually invented using the same base as White willow extract, many purists and natural health enthusiasts prefer to use White willow extract, which is considered to be nature’s aspirin.

Yohimbe is an alkaloid and the active ingredient of a medicinal herb also known as Pausinystalia yohimbe, formerly named Corynanthe yohimbe. It is noted as a stimulant drug and also as an aphrodisiac. While the medicinal community has conducted numerous studies of yohimbe in conjunction with sexual dysfunctions, in veterinary medicine, yohimbine is employed as the antidode to anesthesia stemming from the drug xylazine in large and small animals. In recent times, yohimbine has been found to instigate fat loss in athletes when taken orally. There are also some formulations available, for a significant price, where yohimbine can be directly applied transdermally to adipose tissue, leading to a local reduction. This application is still in experimentation and should not be used without professional assistance.