Chromium Picolinate is derived from picolinic acid and chromium and is sold as a chemical compound as a nutritional supplement deemed to combat chromium deficiencies. Chromium Picolinate has shown some positive effects in treatments of atypical depression, particularly instances where carbohydrate cravings were significantly reduced made the weight loss community become interested. Currently chromium picolinate is being marketed as a supplement supposed to help body builders and athletes to develop muscles, burning excess fat, a claim which could not be verified but is persistent. While chromium is essential in the insulin metabolism, assisting in stabilizing the body’s sugar levels in the blood, the actual effect of chromium picolinate supplement in muscle building humans requires further research. In body building circles, chromium picolinate is deemed an essential part of a proper diet.

Fucoxanthin is a component found in green sea weed that is avidly utilized in promoting excessive weight loss in individuals.

Garcinia Cambogia, which is used for the active ingredient, Hydrocitric Acid or HCA. It is extracted from the garcinia cambogia fruit, similar to an orange. It is commonly used as an appetite suppressant. Hydrocitric acid or HCA is a "lipogenesis inhibitor," which means that it slows down the production of fat from the metabolism of carbohydrates and proteins. This means that more calories are burned as energy and less are turned into stored fat. Studies on animals and humans have shown that HCA can suppress fat production and reduce appetite.

Gymnema Sylvestre is an herb stemming from southern and central India where it has been used for nearly 2000 years as a naturopathic treatment for diabetes.

Hoodia Gordonii is an extract from the Hoodia plant of South West Africa. It is one of the fore runners in weight loss programs. Quenching thirst and providing energy are two of the numerous uses of the plant extract. The extract reduces gastric acid output in the stomach to a large extent, ranging from 40 – 60%. Aside from repressing hunger, Hoodia raises the overall energy levels in the body and will make a person feel completely healthy – both mentally and physically. Hoodia Gordonii is known to be extremely effective and does not have side effects such as dizziness, causing an increase of the heart beat or body temperature and sleeplessness. Hoodia Gordonii, however, should not be used during pregnancy and by nursing mothers.

Resveratrol is a polyphenolic compound that is found in peanuts, the skin of red grapes, red wine, purple grape juice and some varieties of berry. It is classified as polyphenol because of its chemical structure. When taken orally, resveratrol is well absorbed by humans but its low bioavailability makes it rapidly metabolized and then eliminated so that it does not remain in the body for very long. Most of the testing that has been done on resveratrol has not been done on humans so relatively little is known about its effects on the human body. It is claimed that one of the plants resveratrol comes from is called polygonnum cuspidatum and it is used in traditional Asian medicines that treat heart and liver conditions. It has been shown to protect against diabetes-induced damage to blood vessels and also inhibits the growth of tumors and angiogenesis.