Forskolin is derived from the Indian coleus plant, coleus forskohlii and is a labdane diterpene, with antibacterial, anti-protozoal, anti-inflammatory and antifungal properties. Terpene are hydrocarbons, for instance, Vitamin A is a terpene. Forskolin is used to raise cyclic adenosine monophosphate (cAMP) levels in blood, which is an important messenger for multiple biological processes. In humans, cAMP is associated with the management of sugar, lipid and glycogen metabolism, as well as the intracellular signal transduction, including the transfer of effects of glucagon and adrenaline, two essential hormones. Forskolin is deemed a vasodilator, relaxing the smooth muscle tissue within vessel walls, essentially lowering blood pressure. In body building perspective, effects of forskolin in clinical studies have shown that it significantly increases lean muscle mass, bone mass and testosterone levels.

Tribulus Terrestris is an invasive species and noxious weed, but also a flowering perennial plant that is native to warmer to tropical regions of Europe, south of Asia, Africa, north of Australia and recently naturalized in both of the Americas. Historically, the Tribulus terrestris was recognized by the traditional Chinese medicine and the Indian ayurveda. Because of the increases in testosterone levels, also dihydrotestosterone and dehydroepiandrosterone, Tribulus terrestris was deemed an aphrodisiac, but also a nerve tonic and diuretic. Protodioscin was identified as the active chemical in T. terrestris, which is a relative to DHEA. These traits have made this supplement very popular with the body building community, and also why it was used in Biotest Alpha Male,Tribulus terrestris is used as a promoter of a stable libido function and to augment the muscle tone.

Vitex agnus-castus is commonly called vitex. It is also known by its other names such as chaste tree, chasteberry or monk’s pepper. It is plant which is native to the Mediterranean region. Since it has aromatic foliage and flowers, it is cultivated in warm and subtropical regions. In Africa, vitex is a traditional but little known plant. It boosts of food security and also has the potential of improving nutrition. It is also used for foster rural development and it also supports sustainable land care. During pregnancy, the usage of vitex agnus-castus might increase the chance of complications. Therefore, it should be avoided during pregnancy. As it have effects on the testosterone levels, male body builder’s use vitex agnus-castus as a supplement but only as a secondary component.