20-Hydroxyecdysone which is commonly known as 20E or ecdysterone is one of the most common molting hormones found in crabs, insects etc. It can also be described as an ecdysteriod hormone. This hormone helps in controlling the molting and change of arthropods. 20E can achieve all this because it occurs naturally. Various plants also have this hormone. This helps the plants in disrupting the reproduction and growth of insect pests. Physical performance can also be enhanced by using the 20E hormone in certain preparations. Although, research still terms the 20E as a steroid hormone and feels that it has the same possible side effects as a normal steroid. There are still a lot of unanswered questions as to what is the extent of effect of this hormone on mammals and humans. Therefore, much more research is needed before 20-hydroxyecdysone is available for consumption by humans.

6,7 Dihydroxybergamottin is a furanocoumarin. This ingredient is generally present in grapefruit. It is also present in bergamot oil from which it derives its name. To a lesser extent it is even available in other citrus fruits and essential oils. Consuming 6, 7 dihydroxybergamottin supplements have an affect on the metabolism of various pharmaceutical drugs. 6, 7 Dihydroxybergamottin inhibits isforms of cytochrome P450 enzyme, especially CYP3A4. It is because of this feature that the enzyme prevents oxidative metabolism of some drugs, which results in accumulation of the drug in the bloodstream. According to some clinical studies 6, 7 dihydroxybergamottin hamper the body’s ability to digest caffeine, thereby extending its presence in the body. Patients under medication must therefore avoid consuming grapefruit and related supplements.

Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Lagerstroemia Speciosa is a plant that grows commonly in India and countries in Southeast Asia. It can be used for controlling blood sugar. It’s most potent ingredient is corosolic acid. It has the same effect as that of insulin, inducing the transport of glucose from the blood into the body cells. Lagerstroemia Speciosa also helps in weight loss because it enhances the metabolism. It also lowers cholesterol levels and helps maintain the blood pressure. It improves immune system and renal system. It contains Xanthine oxidase, an enzyme involved in catalyzing the oxidation of hypoxanthine to uric acid, this prevents and helps in treating hyperuricemia. Lagerstroemia Speciosa also has antioxidant and antibacterial properties.

Trans-Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens, such as bacteria or fungi. Commercialy it is produced by chemical synthesis and is sold as nutritional supplement. In experiments on mice and rat, it has shown to be beneficial against cancer and blood sugar. Several other beneficial cardiovascular effects have also been reported. Most of these effects are yet to be established on humans.However, in an experiment high doses of Trans-resveratrol is found to significantly lower blood-sugar levels in human beings. In some other studies Trans-resveratrol is found to extend the life span of fruit flies, nematode worms and short-lived fish but it did’nt work on mice.

Tribulus Terrestris refers to an herb used in India and China as traditional medicines for centuries. Tribulus Terrestris contains active compounds known as steroidal saponins, and these are basically found in the leaf. The tribulus consists of furostanol and spirostanol glycosides. People use Tribulus Terrestris for erectile dysfunction as well as low libido. This has gained popularity owing to sports performance improvement. This is available in Russia and Bulgaria as it enhances the testosterone hormone levels, estrogen and DHEA. Tribulus Terrestris supplements taken for four weeks showed no effect on the hormones of the male sex. Preliminary studies heightened the sexual behavior in animals and yet the studies have not confirmed its effect on human beings. However, Tribulus is popular as an aid for sports performance as it shows no effect in exercise performance or body composition. Tribulus do not show any significant change in fat or body weight and this difference can be felt by experiencing strength in the leg press. Conversely, nursing or pregnant women should avoid taking Tribulus.